Takeshi Sugaya Selected Research

Type 1 Angiotensin Receptor

10/2023	Angiotensin II type 1a receptor deficiency alleviates muscle atrophy after denervation.
1/2021	Angiotensin II type 1a receptor loss ameliorates chronic tubulointerstitial damage after renal ischemia reperfusion.
1/2017	Role of angiotensin II type 1a receptor in renal injury induced by deoxycorticosterone acetate-salt hypertension.
1/2012	Glomerular repair retardation via blocking of angiotensin II type 1a receptor pathway in a mouse glomerulonephritis model.
7/2008	Deterioration of atherosclerosis in mice lacking angiotensin II type 1A receptor in bone marrow-derived cells.
12/2007	Angiotensin II type 1a receptor signals are involved in the progression of heart failure in MLP-deficient mice.
11/2006	A possible anti-inflammatory role of angiotensin II type 2 receptor in immune-mediated glomerulonephritis during type 1 receptor blockade.
7/2004	Angiotensin II type 1 receptor interaction is an important regulator for the development of pancreatic fibrosis in mice.
4/2004	Angiotensin II type 1a receptor is involved in cell infiltration, cytokine production, and neovascularization in infarcted myocardium.
2/2004	An essential role for angiotensin II type 1a receptor in pregnancy-associated hypertension with intrauterine growth retardation.

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Takeshi Sugaya Research Topics

Disease

22	Fibrosis (Cirrhosis) 10/2023 - 02/2001
22	Chronic Renal Insufficiency 01/2023 - 11/2002
21	Acute Kidney Injury (Acute Renal Failure) 03/2024 - 10/2006
16	Diabetic Nephropathies (Diabetic Nephropathy) 04/2021 - 11/2005
14	Inflammation (Inflammations) 01/2024 - 05/2004
11	Proteinuria 02/2016 - 11/2002
10	Ulcerative Colitis 01/2024 - 07/2016
10	Hypertension (High Blood Pressure) 01/2022 - 02/2004
10	Hypoxia (Hypoxemia) 01/2021 - 11/2007
10	Kidney Diseases (Kidney Disease) 02/2014 - 12/2003
9	Neoplasms (Cancer) 04/2023 - 07/2003
9	Ischemia 01/2021 - 03/2002
8	Chronic Kidney Failure (Chronic Renal Failure) 04/2016 - 11/2005
7	Type 2 Diabetes Mellitus (MODY) 01/2022 - 09/2006
5	Necrosis 11/2019 - 12/2003
5	Reperfusion Injury 11/2019 - 09/2006
5	Hemorrhage 01/2018 - 10/2006
5	Glomerulonephritis 01/2012 - 09/2005
4	Wounds and Injuries (Trauma) 04/2024 - 04/2009
4	COVID-19 10/2023 - 03/2023
4	Sepsis (Septicemia) 06/2023 - 05/2009
4	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 03/2023 - 10/2018
4	Body Weight (Weight, Body) 04/2021 - 12/2003
4	Crohn Disease (Crohn's Disease) 01/2021 - 01/2017
4	Cardiovascular Diseases (Cardiovascular Disease) 05/2018 - 05/2013
4	Ureteral Obstruction 06/2012 - 06/2004
3	Colitis 01/2024 - 01/2022
3	Hyperglycemia 11/2022 - 02/2014
3	Sclerosis 04/2021 - 01/2017
3	Liver Cirrhosis (Hepatic Cirrhosis) 06/2019 - 07/2008
3	Hepatocellular Carcinoma (Hepatoma) 06/2019 - 04/2010
3	Liver Diseases (Liver Disease) 06/2019 - 01/2008
3	Myocardial Infarction 01/2016 - 04/2004
3	IGA Glomerulonephritis (IGA Nephropathy) 07/2011 - 09/2005
3	Septic Shock (Toxic Shock Syndrome) 12/2010 - 05/2009
3	Disease Progression 12/2007 - 03/2005
2	Abdominal Pain (Pain, Abdominal) 04/2024 - 01/2021
2	Communicable Diseases (Infectious Diseases) 11/2023 - 06/2023
2	Starvation 07/2022 - 06/2021
2	Hyperlipidemias (Hyperlipidemia) 01/2022 - 04/2021
2	Obesity 04/2021 - 01/2016
2	Chronic Hepatitis (Chronic Active Hepatitis) 06/2019 - 03/2005
2	Myocardial Ischemia (Ischemic Heart Diseases) 05/2015 - 06/2012
2	Cardiomyopathies (Cardiomyopathy) 06/2012 - 07/2002

Drug/Important Bio-Agent (IBA)

64	Fatty Acid-Binding ProteinsIBA 03/2024 - 03/2003
32	Biomarkers (Surrogate Marker)IBA 11/2023 - 03/2003
16	Angiotensin IIIBA 01/2017 - 02/2001
15	Type 1 Angiotensin ReceptorIBA 10/2023 - 02/2001
14	Proteins (Proteins, Gene)FDA Link 01/2020 - 11/2002
14	CreatinineIBA 02/2016 - 03/2005
13	AlbuminsIBA 04/2021 - 01/2004
7	Nonesterified Fatty Acids (NEFA)IBA 02/2016 - 11/2002
6	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 11/2011 - 05/2003
5	Cisplatin (Platino)FDA LinkGeneric 06/2021 - 01/2008
5	Urea (Carbamide)FDA LinkGeneric 03/2016 - 10/2006
5	Messenger RNA (mRNA)IBA 12/2013 - 11/2006
4	SteroidsIBA 10/2023 - 02/2010
4	Blood Glucose (Blood Sugar)IBA 01/2022 - 02/2016
4	AntioxidantsIBA 12/2019 - 01/2011
4	SaltsIBA 01/2018 - 10/2013
4	Angiotensin Receptor AntagonistsIBA 09/2010 - 10/2005
4	NitrogenIBA 01/2010 - 10/2006
4	ReninIBA 07/2006 - 10/2002
3	Lipocalin-2IBA 03/2024 - 12/2010
3	C-Reactive ProteinIBA 10/2023 - 01/2017
3	AngiotensinogenIBA 01/2023 - 02/2004
3	Fatty Acids (Saturated Fatty Acids)IBA 01/2022 - 01/2009
3	EnzymesIBA 01/2021 - 09/2005
3	Adenine FDA LinkGeneric 11/2017 - 12/2013
3	Contrast MediaIBA 05/2015 - 03/2006
3	Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA 06/2012 - 12/2003
3	CytokinesIBA 11/2011 - 01/2011
3	Telmisartan (Micardis)FDA Link 09/2010 - 10/2008
3	candesartan cilexetil (Amias)FDA Link 10/2005 - 03/2002
2	Amino Acids FDA Link 01/2024 - 01/2017
2	Dextran SulfateIBA 01/2024 - 01/2022
2	Histones (Histone)IBA 11/2023 - 06/2023
2	Immunologic Factors (Immunomodulators)IBA 10/2023 - 11/2019
2	Mesalamine (Mesalazine)FDA LinkGeneric 10/2023 - 11/2021
2	Neutralizing AntibodiesIBA 03/2023 - 01/2008
2	Xanthine DehydrogenaseIBA 01/2022 - 05/2018
2	Liraglutide FDA Link 01/2022 - 04/2021
2	Glucagon-Like Peptide-1 ReceptorIBA 01/2022 - 04/2021
2	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2021 - 06/2011
2	salicylhydroxamic acid (SHAM)IBA 12/2019 - 10/2010
2	Adalimumab (Humira)FDA Link 10/2019 - 05/2018
2	AldosteroneIBA 10/2019 - 01/2018
2	acarboxyprothrombin (PIVKA)IBA 06/2019 - 04/2010
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2019 - 01/2018
2	Glucose (Dextrose)FDA LinkGeneric 01/2018 - 12/2016
2	PalmitatesIBA 12/2016 - 09/2011
2	Hexosaminidases (Hexosaminidase)IBA 04/2016 - 11/2011
2	Reactive Oxygen Species (Oxygen Radicals)IBA 10/2013 - 12/2003
2	Immunoglobulin G (IgG)IBA 06/2012 - 01/2008
2	CollagenIBA 06/2012 - 10/2008

Therapy/Procedure

14	Therapeutics 04/2024 - 11/2007
3	Renal Dialysis (Hemodialysis) 05/2013 - 11/2005
2	Intraperitoneal Injections 01/2024 - 07/2004
2	Oral Administration 10/2021 - 02/2016
2	Remission Induction 11/2020 - 04/2019